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Phenotropil® is the caviar of Racetams, also known as Phenylpiracetam. It's unquestionably one of the safest and most effective smart drugs.

It was developed in 1983 behind the iron curtain for soviet cosmonauts. Residents of the Mir space station used it to assuage the anxiety and depression caused by a long-term zero gravity lifestyle.

The Mathematician's Racetam

One of the effects noted by Biohackers who use it for cognitive performance enhancement is that it improves one's mathematical aptitude.

  • I've noticed that my Lumosity scores in math games improved while dosed.

  • A day trader reportedI'm a stock analyst/trader, so I use phenylpiracetam to read for a long time various documents without getting interrupted. It's great for getting a lot of work done that doesn't require you to be totally precise. I say "precise" because it might make you overconfident in some situations because you're so focused and powerful for an extended period of time.

The Athlete's Racetam

  • It is a banned athletic performance enhancing substance; a 1999 Korean study found it increased cold resistance and physical endurance.
  • The most recent study out of Riga, Latvia concluded that it helped weight gain. 
  • In addition to these findings, research has shown that rats injected with Phenylpiracetam showed improved motor functions (velocity and distance).

Athletes use Phenotropil to enhance sports performance.

Scientific Research

On Pubmed you can find 6 clinical trials which evaluated Phenylpiracetam in humans. Since it's discovery there have been various studies showing its efficacy as a treatment for those suffering from cognitive decline due to natural reasons.

  • A 2014 study found it was helpful for those suffering from epilepsy: Phenotropil reduced the frequency of seizures and improved cognitive function in the absence of epileptiform EEG abnormalities.
  • Oddly, a 2016 study indicated that taking Phenotropil would help one to maintain work capacity if exposed to radiation.

Mechanism of Action

It's mechanism mirrors that of Piracetam...

  • Although, it appears to be better at crossing the blood brain barrier than Piracetam.
  • Ampakinic, Ampakines are so effective at increasing our awareness of the world around us that DARPA has investigated them for military applications.
  • It modulates cytokine levels.
  • It's a cerebral mitochondrial hack according to recent study: At the same time, the nootropic activity of [citicoline, phenylpiracetam] was comparable to their effect on the functional state of mitochondria in neocortical neurons...


Semax by  
Selank® 0.15%  
  • ACh Precursor, for many Biohackers it's a good idea to supplement your choline intake simultaneous with dosing racetams. 
  • The CILTEP Stack and Racetams have synchronistic actions. Many biohackers report that it nicely compliments the 'social racetam' Aniracetam. Although the three together create an undesirable sensation.
  • Modafinil is actually my favorite thing to combine with Phenylpiracetam. The two together I do not find overstimulating or anxiety inducing but if I combined them not more than twice a week; the focus zone of relentless productivity they put me into is unequaled.
  • Semax  in combination with Phenylpiracetam  may make you scary smart. A Biohacker who thoroughly experimented with both reportedBy the way, Phenotropil works wonders when I take it with Semax. Has anyone experienced that or it's just me?
  • Semax and Selank are a highly renowned stack in elite Biohacker circles. Selank is the one Semax cofactor that is supported by the published scientific research. An American Biohacker reported I had stacked it with selank a few days back, and took a very small dose of ritalin (2.5mg), and went on the most productive 5 hours I had in the last year.

If I were going to shell out the cash for Phenotropil®, I would combine it with these two potent cofactors, and then I would invent faster than light travel.

Usage and Dosage

Dosage 100-200 milligrams daily for cognitive enhancement. 500 milligrams daily is high dosage.

Usage It's an ideal smart drug with it's effect half life of 4-5 hours. So you'll want to take a capsule or two in the morning and one in the mid-afternoon. Do not exceed 700mg (7 pills) per 24 hours.


Phenylpiracetam can be officially used both for healthy people with following On-Label Indications:

  • Extreme work conditions e.g. excessive intellectual or physical requirements
  • As a study aid for concentration improvement.
  • Mild and moderate depressions
  • Chronic fatigue syndrome

Side Effects

  • Side effects are quite rare (<10%) and usually occur in the first three days after which they disappear. They include irritability, psycho-motor excitation and high blood pressure. 
  • The only negative side effects reported consistently about it is choline headaches if you dose too much without supplementing an ACh precursor. 

Risk Grade: A-

Number of Clinical Trials: 6

  • Phenylpiracetam is regarded amongst Biohackers as one of the best smart drugs, it's molecularly very similar Piracetam.
  •  It has a handful of clinical trials; a few of them recent, all of them Russian.
  • Online you can find many veteran Biohackers highly praising it.
  • One Biohacker took Phenylpiracetam for 3 months and reportedWhen I started phenylpiracetam I had some bad side effects from it. I tried two different online sellers of powdered phenylpiracetam (they are not the most popular sources, but they are still well known sources) , and after a few days of uses I would get a strange chest pain and difficulty sleeping. I almost discontinued my usage of this nootropic until I decided to use the original branded phenylpiracetam called Phenotropil. This is the one I have been using for the past three months and I haven't experienced any side effects from it.
  • Unfortunately, it doesn't deserve get a higher grade because of the relative lack of human clinical trials done specifically on Phenylpiracetam at labs and universities around the world.

Country of Manufacture: Russia

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Phenylpiracetam as a Nootropic: The Expensive Linear Thought Promoting Racetam

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