Pharmaceuticals

My thoughts on Mifepristone, the Abortion Pill, Up to 98% effective when used within 8 weeks of pregnancy.

I have not nor do I anticipate using it to have an abortion. I also realize it's a little weird for me as a guy to be doing a video about women's health. However, it's actually relevant to the other sex and contraception Biohacks I've discussed.

And it's consistent with my moral philosophy, I'll explain why later...

Mildronate modulates and improves the function of the heart which has a number of downstream performance-enhancing effects both for our physical and mental capacities.

Meldonium, or Mildronate, is prescribed to treat “different heart and vascular diseases,” according to the Latvian manufacturing company’s website, though it also notes that the drug can improve the “physical capacity” of healthy people. It increases blood flow, which improves exercise capacity in athletes.

Performance Enhancer

Off – label use of Meldonuim in healthy people: increasing exercise tolerance, learning, memory, and even sexual function. One athletic Biohacker reported enthusiastically

"I play ice hockey, tennis and I do weights training and yoga. I have personally taken Meldonium... before weights and yoga training... before ice hockey, and the benefits are immediate : more energy, no hunger, feeling light, as if my body was not heavy, also feeling really concentrate and aware and brain's functions seems enhanced. I could also add that this drug, make you not wanna lose, seems like it has a mental effect that keep you pushing more and refusing to lose or giving up and makes you wanna give your best until the end even in a losing game/match up."

Banned from the Olympics

Wada (World Anti-Doping Agency) found “evidence of it's use by athletes with the intention of enhancing performance” by virtue of carrying more oxygen to muscle tissue.

The decision to add Meldonium to the banned list was approved on September 16th, 2015, and it came into effect on January 1st, 2016. Wada had spent the previous year monitoring the drug before adding it to the banned list.

Meldonium gained popularity after Maria Sharapova, a famous tennis player, from Russia, said that she has been taking this drug for the last 10 years for health reasons. Also, a number of other world and Olympic champions admitted to taking it...

Pharmaceuticals - Page 2 - Limitless Mindset

Semen Elistratov

Maria Sharapova

Ekaterina Bobrova

Eduard Varganov

Aleksey Lovchev

Abeba Aregawi

• World record holder in short track – Semen Elistratov
• Olympic champion figure skater – Ekaterina Bobrova
• Racing cyclist from team Katyusha – Eduard Varganov
• World champion weightlifter Aleksey Lovchev
• World champion runner from Sweden – Abeba Aregawi

Although professor Michael Joyner of the Mayo Clinic expressed some skepticism that it was a real hardcore athletic Biohack: 

"Evidence is lacking for many compounds believed to enhance athletic performance. Its use has a sort of urban legend element and there is not much out there that is clearly that effective. I would be shocked if this stuff [meldonium] had an effect greater than caffeine or creatine...”

Research

On Pubmed, you can find 25 clinical trials which evaluated it in humans. To summarize the findings

• The most recent trial done in 2016 evaluated it in healthy Chinese people. The study called Mildronate is an agent for cardioprotection and neuroprotection.
• A study of 49 patients called it an Adaptogen and found that it made the Russian winter a bit more sufferable and improved quality of life.
• It aids recovery from myocardial ischemia.
• Another 2014 study of middle-aged and elderly evaluated the effect of oxidative stress on meldonium, hemodynamics and quality of life of patients with cardiovascular disease (CVD) in extreme climatic conditions (summer heat). It also concluded that it had an adaptogenic effect, it improved response to oxidative stress 
• A recent trial of 140 patients Early use of meldonium decreases probability of emergence of fatal arrhythmias and improves prognosis of hospital stage of rehabilitation of patients with acute coronary syndrome.

The evidence is better for its physical performance enhancement effects, evidence of its potency as a cognitive enhancer is not significant. It won't be my go-to Russian smart drug.

Side Effects

The recent Chinese study reported No serious adverse events were observed. A 2015 trial of 67 Russians agreed No side effects were registered during the course of mildronate treatment.

Like Semax and Cerebrolysin, Mildronate is on the Russian List of Vital & Essential Drugs.

Country of origin: Latvia

Biohacker Review: Overcoming Sleep Deprivation

I hadn't used Modafinil in quite some time, I'd just received an assortment of Eurogics which I decided to use to offset a night of bad sleep. Which I don't recommend generally, Nootropics should not be used regularly to cope with insomnia, but I suffer from insomnia infrequently and Modafinil can really make a big difference when you're sleep-deprived.

My personal policy on sleep deprivation is that I wake up early, get to work, and do my best to power through the day. I emerged from light and dissatisfying slumber around 5:30 AM after tossing and turning for hours while thoughts raced through my mind. Modafinil typically takes an hour or sometimes two to kick in for me, so I took a full 200-milligram capsule of MODAWAKE® and tried to go back to sleep. The Modafinil kicked in as expected, it's a kind of cool sensation to feel the Modafinil begin to take effect as you are halfway between the dream world and waking life. I cuddled with my wife for a bit and got up.

Biohacker review: We took Oxytocin for Valentine’s Day and there was blood…

Yes, really! For Valentine’s Day last week, my girlfriend and I took pharmaceutical-grade exogenous Oxytocin from RUPharma in Moscow (quite literally from Russia with love!) and it made me bleed. I’ll tell the story but first I’d like to explain why I thought it might be a good idea to supplement Oxytocin…

The enigmatic love molecule, Oxytocin is reputed as a sex hack to heat things up in the bedroom...
But my research led me to believe that in this unromantic age of Tinder and hookup culture, it’s much more useful as a biohack for meaningful monogamy.

Biohacker Review: NANOTROPIL NOVO® is next-level Phenylpiracetam

I got my hands on a package and have been using it on and off for a few weeks. I cycled off my daily-driver Nootropic, Nicotine, when I first went on it because wanted to more accurately gauge its effects. It's a quintessential cognitive enhancer...

• It enhanced my technical problem-solving capacities, which helped me get through a redesign and revamp of my website.
• It sharpened my memory and grasp of vocabulary a bit.
• I had words on the tip of my tongue less.
• Recently I've developed moderate Tinnitus (which probably has something to do with excessive news binging this crazy year) which caused some sleep deprivation. 200 milligrams helped some with sleep deprivation, but addressing the Tinnitus with meditation made a bigger difference.

Your one-stop store for the best Russian nootropics, medicines, and anti-aging agents

Russia has been a powerhouse of pharmacological research and development since the fall of the Soviet Union. RUPharma (the parent company of EuropeChemist.com and NootropicsBase.com) reliably ships a number of unique Nootropics and performance enhancers from warehouses in central Asia, Singapore, Dubai, and domestically in the USA.

Biohacker Review: The Caviar of Russian Nootropics

I've been researching Russian Nootropics and with Semax, more than any other Nootropic ingredient I've researched, I kept coming across Biohackers saying that it's the best smart drug they've ever tried.

Biohacker Review: A happiness-hacking antidepressant (but not for stoics)

The anecdotal reports of Tianeptine led me to believe that it's an antidepressant with cumulative effects. So I've been taking two little capsules of Tianeptine a day and it's a pretty subtle effect but I think I like it, although I didn't experience any pronounced cumulative effects.

It adds a background hum of happiness. The best way I can describe it is kind of like rolling; if you've ever done good ecstasy or MDMA and you just had this feeling of inner happiness and satisfaction. It's like that, although not to such an intense degree minus the potent pro-social effects of MDMA. I didn't find myself being impetuously affectionate with everyone. The effect half-life seems a little short, I notice a subtle optimism for about 3-4 hours after dosing.

Biohacker Review: Stacking Piracetam+Vinpocetine

This is a combination of Piracetam and Vinpocetine. I've been using it for about a month. One of the nice things about Racetams is that you can usually ascertain their Nootropic effect relatively rapidly.