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It's especially useful to our brains in the synthesis and release of the neurotransmitter acetylcholine by neurons.
Choline, a water-soluble nutrient, is essentially one step removed from the real nootropic, Acetylcholine, for which it is a chemical precursor. Choline itself cannot travel across the blood-brain barrier to become Acetylcholine (which we'll refer to from now on as ACh), while Choline bitrate is somewhat more effective in crossing it, and Alpha GPC freely moves from the bloodstream into the brain.
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