The Gut-Brain Connection with Gabe Dough of Good Bru
| Ⓒ By Jonathan Roseland |
I'm not a doctor, medical professional, or trained therapist. I'm a researcher and pragmatic biohacking practitioner exercising free speech to share evidence as I find it. I make no claims. Please practice skepticism and rational critical thinking. You should consult a professional about any serious decisions that you might make about your health. Affiliate links in this article support Limitless Mindset - spend over $300 and you'll be eligible to join the Limitless Mindset Secret Society.
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The gut-brain connection is deeper, weirder, and far more literal than we ever imagined. For years, we’ve been told that our 'gut feeling' is just a metaphor for intuition. But recent science suggests that your gut is actually a 'second brain'—a complex neural network of 100 million neurons that can operate entirely on its own, independent of the one in your skull.
We aren't just talking about digestion; we’re talking about a bidirectional superhighway where bacteria in your colon produce up to 90% of your body’s serotonin and significantly influence your levels of GABA, the primary neurotransmitter for calm. Essentially, the 'critters' in your gut might be the master puppeteers of your mood, your sleep, and even your cognitive clarity.
But as the market for 'gut health' explodes, the gap between marketing claims and clinical reality is widening. I interview Gabe Dough, the founder of Good Bru.

His product bridges that gap using a specific combination of prebiotics and a resilient probiotic strain known as BC30, which I've been using...

Mentioned here
Organic Agave Inulin - A prebiotic fiber validated by 19 human scientific papers
Bacillus coagulans GBI-30 (BC30) - a super-probiotic validated by +50 human clinical studies
Lactobacillus Reuteri (pitched by a 65-year-old sexpert) for boosting Oxytocin
DIY your own probiotic yogurt - Get a yogurt maker for culturing
Probiotics for PICOS: Effects of Synbiotic-Containing Bacillus coagulans (GBI-30) on the Cardiovascular Status of Patients With Polycystic Ovary Syndrome: A Triple-blinded, Randomized, Placebo-controlled Study.
My research on fertility optimization: Decode Your Genome with Personal Genotyping for Precision Fertility Optimization
Self-quantification: personal genomics and gut microbiome testing
Probiotics for protein absorption: Probiotic Bacillus coagulans GBI-30, 6086 Improves Protein Absorption and Utilization.
Probiotics for children: Bacillus coagulans GBI-30, 6068 decreases upper respiratory and gastrointestinal tract symptoms in healthy Mexican school-aged children by modulating immune-related proteins.
Probiotics for Psoriasis: Transforming Psoriasis Care: Probiotics and Prebiotics as Novel Therapeutic Approaches out of Cluj-Napoca, Romania (where I once spent a couple of weeks)
Probiotics for bone loss: Bacillus coagulans ameliorates inflammatory bone loss in post-menopausal osteoporosis via modulating the "Gut-Immune-Bone" axis
Probiotics for irritable bowel syndrome: Efficacy and safety of Bacillus coagulans LBSC in irritable bowel syndrome: A prospective, interventional, randomized, double-blind, placebo-controlled clinical study [CONSORT Compliant]
Weird gut science: Personality transplant via gut microbes, microbial hijacking of craving control, and the brain as "PR department" for the gut
Probiotic cofactors: HMB and NMN for boosting NAD+ (potentially)
"Getting your gut health right gives you the right to architect your personality and therefore your reality..."
Is how I concluded the interview with Gabe, and I like what Good Bru is about, so I've included them as a Limitless Mindset Secret Society recommended vendor. Pick up over $300 worth of product from them (or mix and match with other Secret Society vendors) and get a helpful free Biohacking consultation with me.
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